Where do the biospecimens come from?
Trans-Hit Bio does not collect or store biospecimens. We partner with academic and hospital-based biobanks and other clinical collection sites that are subject to local IRB approval. By functioning as an intermediary between researchers seeking biospecimens and recognized biospecimen providers and biobanks, THB sources and provides you with the highest quality biospecimens for your research requirements.
What kinds of data can be collected about the biospecimens requested?
At THB we understand the importance of data related to your biospecimens. A vast array of data could be provided with biospecimens sourced by THB:
• Time of collection
• Medical history related to disease
• Pathology data (surgical pathology, histopathology, and staging)
• Follow-up data (longitudinal studies)
THB’s partners provide associated data that is de-identified and HIPAA/GDPR-compliant.
Do you provide samples from donors with specific diseases such as cancer, infectious diseases, and others?
Yes. Our network of approved biobanks and clinical collection sites is extensive. THB sources your required samples from a variety of disease-specific collections and institutional repositories giving you access to a broad range of disease-specific biospecimens.
Does THB have a catalog of available biospecimens?
We do not maintain a catalog or inventory of available biospecimens. This is because the rapid advancement of research and changes in research needs makes such a list of biospecimens obsolete and limiting to you as researchers. We think we would be doing a disservice to researchers seeking biospecimens by providing them with a catalog rather than listening to their research requirements and sourcing the ideal biospecimens required for their specific research. Our network of providers ensures that our clients have access to a variety of retrospective samples as well as customized prospective collections. Ultimately, our role at THB is to go beyond cataloging to obtain the biospecimens you need regardless of the abundance or rarity of the specimens you are looking for.
Do you charge for sample feasibility assessment?
There is no charge for feasibility assessment. At the heart of THB’s service is our commitment to listening to your research needs and finding the right biobank or clinical collection site to source you with the highest quality biospecimens required by the specifics of your research.
If I acquire samples from outside the US, will the pathology diagnosis differ?
Differences in diagnosis of pathologies, such as the classification of disease progression, can differ widely depending on where the samples are collected. This is yet another reason why THB’s policy on traceability of collection sites is crucial.
Are the samples provided by THB’s biospecimen sources approved by an ethics committee or IRB?
Yes. All our partners collect and provide samples under the approval of umbrella ethics committees or boards. In the case of prospective biospecimen samples, such as customized or fresh tissue, a specific approval is sought from recognized IRBs.
At THB, we share your concern for obtaining institutionally reviewed and monitored human biospecimens and we have built a network of supplying biobanks and clinical collections sites that share in this vision of ethical biomedical research.
Do donors of the biospecimens sourced by THB’s providers consent to the collection of their tissue or fluid for the purpose of research?
Most of the biospecimens collected or stored in biobanks for Trans-Hit Bio’s clients are collected through a process which includes regulated informed consent. In some countries, such as the USA, remnant samples from diagnostic laboratories and biological waste from surgeries can be awarded a waiver of consent by local IRB standards, in which case donor consent is not required. The use of such samples, however, is still regulated by strict IRB approval.
What are the costs associated with acquiring biospecimens for research?
At THB, we adhere to the notion that human tissue is not merchandisable. The costs involved with acquiring biospecimens for research relates directly to the costs involved in collecting, analyzing, handling, storing, and transporting biospecimen samples as per the requirements of any given research study. It follows that the costs associated with acquiring samples depends on the type of preparation and the depth of associated data required for the biospecimens in question. At THB, our expert advisors are happy to listen to your specific needs and discuss the feasibility of your biospecimen request to provide you with a detailed quote customized to your research requirements.
How long will it take to receive our requested biospecimens?
THB acts as an intermediary, streamlining the process of obtaining the highest quality samples. Delays in receiving biospecimens depend on whether your research requires retrospective or prospective samples, but in all cases specimen samples are transported from the biobank or clinical collection site directly to the laboratory where the research will take place. Eliminating extra logistical steps ensures the quality of your samples is exposed to less risk before arriving to you. Samples can be transported fresh, frozen, or at ambient temperature depending on the specifications required for your research.
What couriers are used to transport the biospecimens?
Trans-Hit Bio supervises all shipping logistics and ensures the samples arrive in good shape to their destination. To ensure the highest standards of biospecimen transport, we work with experienced and reputed couriers.
Is it possible to return samples and, if so, what is the policy?
Yes, it is possible to return samples providing that their failure to meet specifications is not the result of mishandling by the end-user. After reception of the biospecimens, and within a specified time limit, the end-user must provide written notice to Trans-Hit Bio of any failure of the biospecimen to meet specified requirements. Following this procedure, Trans-Hit Bio will make reasonable efforts to replace the unqualified specimens with biospecimens that conform to the specifications, within a reasonable time.