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  • AS-144

    Disease

    Hepatitis B

    Type and Number of Samples

    up to 10 - Frozen Liver Tissue (≥ 500 mg) Or FFPE blocks

    Specific Requirements

    Subjects must have positive serology for Anti-HBsAg (Hep B surface antigen)

    • Liver Normal Adjacent Tissue only
    • HBV +ve, can include HCC resection normal adjacent tissue
    • Samples from either NUC +/- subjects (subjects with NUC treatment are preferred)
    • Sample from subjects diagnosed with HBV only, no co-infection

    Associated Data Required

    Age, Gender

    • HLA allele
    • Treatment history for chronic HBV (nucleos(t)ide analogue NUC/PEG-IFNa/other)
    • Hepatocellular carcinoma status/history
    • HBsAg quantitation - HBsAg +/- status
    • HBV DNA quantitation - Viral Genotype
    • ALT (liver transaminases) levels - Transient elastography/ Fibroscan (kPa)
  • AS-143

    Disease

    Triple-Negative Breast Cancer (TNBC)

    • Retrospective

    Type and Number of Samples

    up to 150 - 1 tumor FFPE block and 1 matched normal FFPE block

    Specific Requirements

    Confirmed diagnosis of TNBC - Primary tumors only - Resections only

    • Any grade - Stage ≤ III
    • Confirmed hormone receptor-negative status: ER-/PR-/HER2-

    Associated Data Required

    Age, Gender

    • ER, PR, HER2 expression status
    • TNM and Cancer Stage, Grade,
  • AS-142

    Disease

    Myelofibrosis

    Type and Number of Samples

    FFPE Blocks - 15 samples

    Specific Requirements

    Retrospective samples

    • Tissues from Bone marrow trephines
    • Tissues from both primary and secondary (i.e. metastatic) tumors accepted
    • Decalcification method cannot contain acid
    • Bone marrow sample size: > 3mm (preferably 10 mm)
    • Sections to be mounted on Superfrost Ultra Plus® slides, one section per slide
    • 3 unstained sections to be delivered first for testing/screening by the End User

    Associated Data Required

    Age, Gender

    • Cancer Stage
    • Sample collection site
    • Anatomical site of tissue collection (eg. organ)
  • AS-141

    Disease

    Candida albicans infection

    Type and Number of Samples

    FFPE Blocks

    • 30 samples

    Specific Requirements

    Skin tissues

    • Treated or untreated subjects

    Associated Data Required

    Age, Gender

    • Diagnosis method
  • AS-140

    Disease

    Systemic Lupus Erythematosus (SLE) Nephritis

    • Healthy Controls

    Type and Number of Samples

    20

    • Urine sample (>30ml)

    Specific Requirements

    Confirmed diagnosis of SLE according to the American College of Rheumatology (ACR) criteria

    • Confirmed diagnosis of Class III/IV Lupus Nephritis
    • Proteinuria ratio > 1.0, based on 24h urine collection

    Associated Data Required

    Age, Gender

    • ACR criteria used for SLE diagnosis
    • Protein-urea content
  • AS-139

    Disease

    Lung Cancer

    • Healthy Controls

    Type and Number of Samples

    Plasma - 400 Lung Cancer / 400 Healthy controls

    Specific Requirements

    ≥ 40 years of age only

    • Smoking history of 20 packs / year (
    • Similar age distribution between male and female subjects

    Associated Data Required

    Age, gender

    • Smoking history (packs/year)
    • Date of sample collection
  • AS-137

    Disease

    Fabry Disease

    Type and Number of Samples

    Frozen Tissue and FFPE Tissue - 10 subjects

  • AS-131

    Disease

    ADENOVIRUS INFECTION

    Type and Number of Samples

    TISSUE: FFPE; 2 samples