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SELECTED PAST STUDIES - Central Nervous System Diseases - Central Nervous System Diseases

Study

Disease

type & number of samples

Specific Requirements

associated data required

TBI-1

Traumatic Brain Injury

Plasma

Prospective

More than 250 subjects

  • Glasgow Coma Scale Score between 3 to 15
  • Up to 4 samples collected per subject at different time points after head injury within:
    • 0-3 hours
    • 8-12 hours
    • 24-48 hours
    • 48-72 hours
  • Age, Gender, Ethnicity
  • Date/Time of initial presentation or injury
  • Cause of TBI
  • Other traumatic injuries
  • Date/Time of blood collection
  • GCS score at admission

MS-1

Multiple Sclerosis

Plasma

Retrospective

More than 30 subjects

2 groups:

  • Patients who had an attack within 12 months after treatment initiation
  • Patients without an additional attack and without significant (over 5) new T1/FLAIR lesions in the brain
  • Treated subjects only
  • Age, gender, ethnicity
  • Duration of the disease

MS-2

Multiple Sclerosis

Frozen Brain Tissue

Retrospective

More than 2 subjects

  • Brain tissue regions:
    • Occipital Cortex
    • Cerebellum
    • Pons
    • Temporal Lobe
    • Basal Ganglia
    • Parietal Lobe
    • Frontal Cortex
    • White Matter
    • Cervical Cord
  • Age, gender, ethnicity
  • Duration of the disease
  • PMI